| Title | Authors | Journal | Year | Keywords (hidden column) |
|---|---|---|---|---|
| Mitochondrial might: powering the peripartum for risk and resilience | Gorman-Sandler E, Wood G, Cloude N, Frambes N, Brennen H, Robertson B, Hollis F | Frontiers in Behavioral Neuroscience | 2023 | |
| Hippo Signaling Mediates TGFβ-Dependent Transcriptional Inputs in Cardiac Cushion Mesenchymal Cells to Regulate Extracellular Matrix Remodeling | Chakrabarti M, Chattha A, Nair A, Jiao K, Potts JD, Wang L, Branch S, Harrelson S, Khan S, Azhar M | Journal of Cardiovascular Development and Disease | 2023 | |
| Pair bonding and disruption impact lung transcriptome in monogamous Peromyscus californicus | Naderi A, Liles K, Burns T, Chavez B, Huynh-Dam KT, Kiaris H | BMC Genomics | 2023 | |
| Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide | Li Y, Eans SO, Ganno-Sherwood M, Eliasof A, Houghten RA, McLaughlin JP | Molecules | 2023 | |
| Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine | Larit F, León F | Plants (Basel) | 2023 | |
| The O-GlcNAc dichotomy: when does adaptation become pathological? | Costa TJ, Wilson EW, Fontes MT, Pernomian L, Tostes RC, Wenceslau CF, McCarthy CG | Clinical Science (London) | 2023 | |
| A Novel Tissue-Specific Insight into Sex Steroid Fluctuations Throughout the Murine Estrous Cycle | Unger CA, Hope MC 3rd, Aladhami AK, Cotham WE, Socia CE, Rice BC, Clegg DJ, Velázquez KT, LaVoie HA, Hollis F, Enos RT | Endocrinology | 2023 | |
| Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency | Piroli GG, Manuel AM, McCain RS, Smith HH, Ozohanics O, Mellid S, Cox JH, Cotham WE, Walla MD, Cascón A, Ambrus A, Frizzell N | Redox Biology | 2023 | |
| To err, K(IR)2 that is, on the side of vasodilation in aging | Bernardino de Paula R, Wenceslau CF, McCarthy CG | American Journal of Physiology - Heart and Circulatory Physiology | 2023 | |
| Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells | Truex NL, Rondon A, Rössler SL, Hanna CC, Cho Y, Wang BY, Backlund CM, Lutz EA, Irvine DJ, Pentelute BL | ACS Central Science | 2023 | |
| Gestational stress decreases postpartum mitochondrial respiration in the prefrontal cortex of female rats | Gorman-Sandler E, Robertson B, Crawford J, Wood G, Ramesh A, Arishe OO, Webb RC, Hollis F | Neurobiology of Stress | 2023 | |
| Delayed cognitive impairments in a rat model of Gulf War Illness are stimulus-dependent | Burzynski HE, Ayala KE, Frick MA, Dufala HA, Woodruff JL, Macht VA, Eberl BR, Hollis F, McQuail JA, Grillo CA, Fadel JR, Reagan LP | Brain, Behavior, and Immunity | 2023 | |
| Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes | Kokinos EK, Tsymbal SA, Galochkina AV, Bezlepkina SA, Nikolaeva JV, Vershinina SO, Shtro AA, Tatarskiy VV, Shtil AA, Broude EV, Roninson IB, Dukhinova M | Viruses | 2023 | |
| CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins | Chen M, Li J, Zhang L, Wang L, Cheng C, Ji H, Altilia S, Ding X, Cai G, Altomare D, Shtutman M, Byrum SD, Mackintosh SG, Feoktistov A, Soshnikova N, Mogila VA, Tatarskiy V, Erokhin M, Chetverina D, Prawira A, Ni Y, Urban S, McInnes C, Broude EV, Roninson IB | Nucleic Acids Research | 2023 | |
| The SARS-CoV-2 spike protein induces long-term transcriptional perturbations of mitochondrial metabolic genes, causes cardiac fibrosis, and reduces myocardial contractile in obese mice | Cao X, Nguyen V, Tsai J, Gao C, Tian Y, Zhang Y, Carver W, Kiaris H, Cui T, Tan W | Molecular Metabolism | 2023 | |
| The Polypharmacological Effects of Cannabidiol | Castillo-Arellano J, Canseco-Alba A, Cutler SJ, León F | Molecules | 2023 | |
| Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification | Saatci O, Akbulut O, Cetin M, Sikirzhytski V, Uner M, Lengerli D, O'Quinn EC, Romeo MJ, Caliskan B, Banoglu E, Aksoy S, Uner A, Sahin O | Cell Death & Differentiation | 2023 | |
| RASSF1 is identified by transcriptome coordination analysis as a target of ATF4 | Zhang Y, Huynh-Dam KT, Ding X, Sikirzhytski V, Lim CU, Broude E, Kiaris H | FEBS Open Bio | 2023 | |
| Structural Basis for Variations in Polo-like Kinase 1 Conformation and Intracellular Stability Induced by ATP-Competitive and Novel Noncompetitive Abbapolin Inhibitors | Chapagai D, Merhej G, McInnes C, Wyatt MD | ACS Chemical Biology | 2023 | |
| One-Pot High-throughput Synthesis of N3-Substituted 5-Arylidene-2-Thiohydantoin Amides and Acids | Whitely C, Li Y | Tetrahedron Letters | 2022 | |
| Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis | Gasparian A, Aksenova M, Oliver D, Levina E, Doran R, Lucius M, Piroli G, Oleinik N, Ogretmen B, Mythreye K, Frizzell N, Broude E, Wyatt MD, Shtutman M | Molecular Biology of the Cell | 2022 | |
| Graphene-incorporated hyaluronic acid-based hydrogel as a controlled Senexin A delivery system | Maturavongsadit P, Wu W, Fan J, Roninson IB, Cui T, Wang Q | Biomaterials Translational | 2022 | |
| Conserved age-related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories | Pilarzyk K, Porcher L, Capell WR, Burbano SD, Davis J, Fisher JL, Gorny N, Petrolle S, Kelly MP | Aging Cell | 2022 | |
| A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria | Kholmukhamedov A, Li L, Lindsey CC, Hu J, Nieminen AL, Takemoto K, Beeson GC, Beneker CM, McInnes C, Beeson CC, Lemasters JJ | Journal of Biological Chemistry | 2022 | |
| Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo | Ding X, Sharko AC, McDermott MSJ, Schools GP, Chumanevich A, Ji H, Li J, Zhang L, Mack ZT, Sikirzhytski V, Shtutman M, Ivers L, O'Donovan N, Crown J, Győrffy B, Chen M, Roninson IB, Broude EV | Proceedings of the National Academy of Sciences of the United States of America | 2022 | |
| Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer | Shonibare Z, Monavarian M, O'Connell K, Altomare D, Shelton A, Mehta S, Jaskula-Sztul R, Phaeton R, Starr MD, Whitaker R, Berchuck A, Nixon AB, Arend RC, Lee NY, Miller CR, Hempel N, Mythreye K | Cell Reports | 2022 | |
| PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance | Tabury K, Monavarian M, Listik E, Shelton AK, Choi AS, Quintens R, Arend RC, Hempel N, Miller CR, Györrfy B, Mythreye K | Life Science Alliance | 2022 | |
| Natural Products Inhibitors of Monoamine Oxidases-Potential New Drug Leads for Neuroprotection, Neurological Disorders, and Neuroblastoma | Chaurasiya ND, Leon F, Muhammad I, Tekwani BL | Molecules | 2022 | |
| The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2 | Nguyen V, Zhang Y, Gao C, Cao X, Tian Y, Carver W, Kiaris H, Cui T, Tan W | Cells | 2022 | |
| Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers | Horst B, Pradhan S, Chaudhary R, Listik E, Quintero-Macias L, Choi AS, Southard M, Liu Y, Whitaker R, Hempel N, Berchuck A, Nixon AB, Lee NY, Henis YI, Mythreye K | Communications Biology | 2022 | |
| Surface Functionalization of Polymer Particles for Cell Targeting by Modifying Emulsifier Chemistry | Isely C, Atube KJ, Cheung CV, Steege CF, Pellechia PJ, Gower RM | ACS Applied Polymer Materials | 2022 | |
| Identification and Biosynthesis of Pro-Inflammatory Sulfonolipids from an Opportunistic Pathogen Chryseobacterium gleum | Hou L, Tian HY, Wang L, Ferris ZE, Wang J, Cai M, Older EA, Raja MRK, Xue D, Sun W, Nagarkatti P, Nagarkatti M, Chen H, Fan D, Tang X, Li J | ACS Chemical Biology | 2022 | |
| Correlational networking guides the discovery of unclustered lanthipeptide protease-encoding genes | Xue D, Older EA, Zhong Z, Shang Z, Chen N, Dittenhauser N, Hou L, Cai P, Walla MD, Dong SH, Tang X, Chen H, Nagarkatti P, Nagarkatti M, Li YX, Li J | Nature Communications | 2022 | |
| Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer | Assidicky R, Tokat UM, Tarman IO, Saatci O, Ersan PG, Raza U, Ogul H, Riazalhosseini Y, Can T, Sahin O | Breast Cancer Research and Treatment | 2022 | |
| GABA(B) receptors in prelimbic cortex and basolateral amygdala differentially influence intertemporal decision making and decline with age | Hernandez CM, McQuail JA, Ten Eyck TW, Wheeler AR, Labiste CC, Setlow B, Bizon JL | Neuropharmacology | 2022 | |
| A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics | Zhang L, Cheng C, Li J, Wang L, Chumanevich AA, Porter DC, Mindich A, Gorbunova S, Roninson IB, Chen M, McInnes C | Journal of Medicinal Chemistry | 2022 | |
| EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers | Cicek E, Circir A, Oyken M, Akbulut Caliskan O, Dioken DN, Guntekin Ergun S, Cetin-Atalay R, Sapmaz A, Ovaa H, Sahin O, Erson-Bensan AE | Oncogene | 2022 | |
| Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q | Park I, Phan TM, Fang J | Cancers (Basel) |
2021 | |
| Heterogeneous Myeloid Cells in Tumors | Dou A, Fang J | Cancers (Basel) | 2021 | |
| Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells | Chapagai D, Ramamoorthy G, Varghese J, Nurmemmedov E, McInnes C, Wyatt MD | Journal of Medicinal Chemistry | 2021 | |
| Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration | Jhanji M, Rao CN, Massey JC, Hope MC 3rd, Zhou X, Keene CD, Ma T, Wyatt MD, Stewart JA, Sajish M | Nature Communications | 2022 | |
| Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE | Craig SN, Baxter M, Chapagai D, Stafford JM, Nurmemmedov E, Altomare D, Wyatt MD, McInnes C | European Journal of Medicinal Chemistry | 2022 | |
| Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies | Saatci O, Huynh-Dam KT, Sahin O | Journal of Molecular Medicine (Berlin, Germany) | 2021 | |
| Mercapto-functionalized polyhedral oligomeric silsesquioxane as a soluble support for the synthesis of peptide thioesters | Perry K, Sui B, Li Y | Tetrahedron Letters | 2021 | |
| Roles of Exosomes in Cardiac Fibroblast Activation and Fibrosis | Hohn J, Tan W, Carver A, Barrett H, Carver W | Cells | 2021 | |
| Propensity to endoplasmic reticulum stress in deer mouse fibroblasts predicts skin inflammation and body weight gain | Zhang Y, Lim CU, Sikirzhytski V, Naderi A, Chatzistamou I, Kiaris H | Disease Models & Mechanisms | 2021 | |
| Attenuated NMDAR signaling on fast-spiking interneurons in prefrontal cortex contributes to age-related decline of cognitive flexibility | McQuail JA, Beas BS, Kelly KB, Hernandez CM 3rd, Bizon JL, Frazier CJ | Neuropharmacology | 2021 | |
| Genomic variation in captive deer mouse (Peromyscus maniculatus) populations | Lucius MD, Ji H, Altomare D, Doran R, Torkian B, Havighorst A, Kaza V, Zhang Y, Gasparian AV, Magagnoli J, Shankar V, Shtutman M, Kiaris H | BMC Genomics | 2021 | |
| Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice | Cao X, Tian Y, Nguyen V, Zhang Y, Gao C, Yin R, Carver W, Fan D, Albrecht H, Cui T, Tan W | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2021 | |
| Regulation of PKR activation and apoptosis during oxidative stress by TRBP phosphorylation | Ukhueduan B, Chukwurah E, Patel RC | The international journal of biochemistry & cell biology | 2021 | |
| Macrophage tumor necrosis factor-alpha deletion does not protect against obesity-associated metabolic dysfunction | Aladhami AK, Unger CA, Ennis SL, Altomare D, Ji H, Hope MC 3rd, Velázquez KT, Enos RT | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 2021 | |
| A strategy for the identification of paracrine regulators of cancer cell migration | Chavez B, Farmaki E, Zhang Y, Altomare D, Hao J, Soltnamohammadi E, Shtutman M, Chatzistamou I, Kiaris H | Clinical and experimental pharmacology & physiology | 2020 | |
| Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation | Aksenova M, Sybrandt J, Cui B, Sikirzhytski V, Ji H, Odhiambo D, Lucius MD, Turner JR, Broude E, Peña E, Lizarraga S, Zhu J, Safro I, Wyatt MD, Shtutman M | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology | 2020 | |
| Obesity-induced TRB3 negatively regulates Brown adipose tissue function in mice | Jeong HW, Choi RH, Koh HJ | Biochemical and biophysical research communications | 2021 | |
| Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling | Vaughn LS, Chukwurah E, Patel RC | The Biochemical journal | 2021 | |
| The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs | Sharko AC, Lim CU, McDermott MSJ, Hennes C, Philavong KP, Aiken T, Tatarskiy VV, Roninson IB, Broude EV | Cells | 2021 | |
| Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer | Siddiqui MA, Gollavilli PN, Ramesh V, Parma B, Schwab A, Vazakidou ME, Natesan R, Saatci O, Rapa I, Bironzo P, Schuhwerk H, Asangani IA, Sahin O, Volante M, Ceppi P | British journal of cancer | 2021 | |
| Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly | Cui BC, Sikirzhytski V, Aksenova M, Lucius MD, Levon GH, Mack ZT, Pollack C, Odhiambo D, Broude E, Lizarraga SB, Wyatt MD, Shtutman M | Biochemical pharmacology | 2020 | |
| Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress | Ackerson SM, Gable CI, Stewart JA | Cell cycle (Georgetown, Tex.) | 2020 | |
| Fabrication of biodegradable particles with tunable morphologies by the addition of resveratrol to oil in water emulsions | Isely C, Stevens AC, Tate GL, Monnier JR, Gower RM | International journal of pharmaceutics | 2020 | |
| Towards resolving the enigma of the dichotomy of resveratrol: cis and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation | Jhanji M, Rao CN, Sajish M | GeroScience | 2020 | |
| Carrier-Free Nanoassembly of Curcumin-Erlotinib Conjugate for Cancer Targeted Therapy | Cheng C, Sui B, Wang M, Hu X, Shi S, Xu P | Advanced healthcare materials | 2020 | |
| Redox-Sensitive Nanocomplex for Targeted Delivery of Melittin | Cheng B, Xu P | Toxins | 2020 | |
| Enhanced Photothermal Therapy through the In Situ Activation of a Temperature and Redox Dual-Sensitive Nanoreservoir of Triptolide | Liu HJ, Wang M, Hu X, Shi S, Xu P | Small (Weinheim an der Bergstrasse, Germany) | 2020 | |
| Mature Vascular Smooth Muscle Cells, but Not Endothelial Cells, Serve as the Major Cellular Source of Intimal Hyperplasia in Vein Grafts | Wu W, Wang C, Zang H, Qi L, Azhar M, Nagarkatti M, Nagarkatti P, Cai G, Weiser-Evans MCM, Cui T | Arteriosclerosis, thrombosis, and vascular biology | 2020 | |
| Modulation of adipocyte size and fat pad weight via resveratrol releasing scaffolds implanted into the epididymal adipose tissue | Murphy KP, Hendley MA, Patterson AT, Hall HE, Carter GJ, Isely C, Gower RM | Journal of biomedical materials research | 2020 | |
| tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation | Avcilar-Kucukgoze I, Gamper H, Polte C, Ignatova Z, Kraetzner R, Shtutman M, Hou YM, Dong DW, Kashina A | Cell chemical biology | 2020 | |
| Regulation of stress-induced hematopoiesis | Anderson GA, Rodriguez M, Kathrein KL | Current opinion in hematology | 2020 | |
| Cognitive Reserve in Model Systems for Mechanistic Discovery: The Importance of Longitudinal Studies | McQuail JA, Dunn AR, Stern Y, Barnes CA, Kempermann G, Rapp PR, Kaczorowski CC, Foster TC | Frontiers in aging neuroscience | 2020 | |
| Scaffold Implant Into the Epididymal Adipose Tissue Protects Mice From High Fat Diet Induced Ectopic Lipid Accumulation and Hyperinsulinemia | Hendley MA, Isely C, Murphy KP, Hall HE, Annamalai P, Gower RM | Frontiers in bioengineering and biotechnology | 2020 | |
| Coordination Analysis of Gene Expression Points to the Relative Impact of Different Regulators During Endoplasmic Reticulum Stress | Zhang Y, Lucius MD, Altomare D, Havighorst A, Farmaki E, Chatzistamou I, Shtutman M, Kiaris H | DNA and cell biology | 2019 | |
| Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy | Mohammed AD, Khan MAW, Chatzistamou I, Chamseddine D, Williams-Kang K, Perry M, Enos R, Murphy A, Gomez G, Aladhami A, Oskeritzian CA, Jolly A, Chang Y, He S, Pan Z, Kubinak JL | Frontiers in immunology | 2019 | |
| CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: Determinants of Response and Synergy with EGFR Inhibition | McDermott MSJ, Sharko AC, Munie J, Kassler S, Melendez T, Lim CU, Broude EV | Cells | 2020 | tag 1, tag2 |
| A Highly Potent TACC3 Inhibitor as a Novel Anti-cancer Drug Candidate | Akbulut O, Lengerli D, Saatci O, Duman E, Seker UOS, Isik A, Akyol A, Caliskan B, Banoglu E, Sahin O | Molecular Cancer Therapeutics | 2020 | |
| Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer | Saatci O, Kaymak A, Raza U, Ersan PG, Akbulut O, Banister CE, Sikirzhytski V, Tokat UM, Aykut G, Ansari SA, Dogan HT, Dogan M, Jandaghi P, Isik A, Gundogdu F, Kosemehmetoglu K, Disdar O, Aksoy S, Akyol A, Uner A, Buckhaults PJ, Riazalhosseini Y, Sahin O | Nature Communications | 2020 | |
| TRB3 regulates skeletal muscle mass in food deprivation-induced atrophy | Choi RH, McConahay A, Silvestre JG, Moriscot AS, Carson JA, Koh HJ | The FASEB Journal | 2019 | |
| Role of transcription-regulating kinase CDK8 in colon cancer metastasis | Liang J, Chen M, Broude EV, Roninson IB | Oncotarget | 2019 | |
| Repurposing suramin for the treatment of breast cancer lung metastasis with glycol chitosan-based nanoparticles | Cheng B, Gao F, Maissy E, Xu P | Acta Biomaterialia | 2019 | |
| Structural insight into substrate and inhibitor discrimination by human P-glycoprotein | Alam A, Kowal J, Broude E, Roninson I, Locher KP | Science | 2019 | |
| Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization | Piroli GG, Manuel AM, Patel T, Walla MD, Shi L, Lanci SA, Wang J, Galloway A, Ortinski PI, Smith DS, Frizzell N | Molecular & Cellular Proteomics | 2019 | |
| Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association | Wang Y, Brady KS, Caiello BP, Ackerson SM, Stewart JA | Life Science Alliance | 2019 | |
| Nicotinamide Augments the Anti-Inflammatory Properties of Resveratrol through PARP1 Activation | Yanez M, Jhanji M, Murphy K, Gower RM, Sajish M, Jabbarzadeh E | Scientific Reports | 2019 | |
| Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice | Oza M, Becker W, Gummadidala PM, Dias T, Omebeyinje MH, Chen L, Mitra C, Jesmin R, Chakraborty P, Sajish M, Hofseth LJ, Banerjee K, Wang Q, Moeller PDR, Nagarkatti M, Nagarkatti P, Chanda A | Scientific Reports | 2019 | |
| Identifying Cancers Impacted by CDK8/19 | Roninson IB, Gyorffy B, Mack ZT, Shtil AA, Shtutman MS, Chen M, Broude EV | Cells | 2019 | |
| HPV16-transformed human keratinocytes depend on SIX1 expression for proliferation and HPV E6/E7 gene expression | Hosseinipour M, Wan F, Altomare D, Creek KE, Pirisi L | Virology | 2019 | |
| Development of microparticles for controlled release of resveratrol to adipose tissue and the impact of drug loading on particle morphology and drug release | Isely C, Hendley MA, Murphy KP, Kader S, Annamalai P, Jabbari E, Gower RM | International Journal of Pharmaceutics | 2019 | |
| Systems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastasis Inducers in Breast Cancer | Uretmen Kagiali ZC, Sanal E, Karayel O, Polat AN, Saatci O, Ersan PG, Trappe K, Renard BY, Onder TT, Tuncbag N, Sahin O, Ozlu N | Molecular & Cellular Proteomics | 2019 | |
| The host response to poly(lactide-co-glycolide) scaffolds protects mice from diet induced obesity and glucose intolerance | Hendley MA, Murphy KP, Isely C, Struckman HL, Annamalai P, Gower RM | Biomaterials | 2019 | |
| Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay | Li J, Ji H, Porter DC, Broude EV, Roninson IB, Chen M | Cells | 2019 | |
| Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition | Chen M, Li J, Liang J, Thompson ZS, Kathrein K, Broude EV, Roninson IB | Cells | 2019 | |
| Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers | Siddiqui A, Gollavilli PN, Schwab A, Vazakidou ME, Ersan PG, Ramakrishnan M, Pluim D, Coggins S, Saatci O, Annaratone L, Hm Schellens J, Kim B, Asangani IA, Rasheed SAK, Marchio C, Sahin O, Ceppi P | Cell Death & Differentiation | 2019 | |
| Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation | Aksenova M, Sybrandt J, Cui B, Sikirzhytski V, Ji H, Odhiambo D, Lucius MD, Turner JR, Broude E, Peña E, Lizarraga S, Zhu J, Safro I, Wyatt MD, Shtutman M | Journal of Neuroimmune Pharmacology | 2019 | |
| The Meisenheimer Complex as a paradigm in drug discovery: reversible covalent inhibition through C67 of the ATP binding site of PLK1 | Pearson RJ, Blake DG, Mezna M, Fischer PM, Westwood NJ, McInnes C | Cell Chemical Biology | 2018 | |
| Insulin Resistance as a Therapeutic Target in the Treatment of Alzheimer's Disease: A State-of-the-Art Review | Benedict C, Grillo CA | Frontiers in Neuroscience | 2018 | |
| hnRNPs binding to the axonal localization motifs of Nrn1 and HMGB1 mRNAs define growth-associated RNA regulons | Lee SJ, Oses-Prieto JA, Kawaguchi R, Sahoo PK, Kar AN, Rozenbaum M, Oliver D, Chand S, Ji H, Shtutman M, Miller-Randolph S, Taylor RJ, Fainzilber M, Coppola G, Burlingame AL, Twiss JL | Molecular & Cellular Proteomics | 2018 | |
| CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases | Liang J, Chen M, Hughes D, Chumanevich AA, Altilia S, Kaza V, Lim CU, Kiaris H, Mythreye K, Pena MM, Broude EV, Roninson IB | Cancer Research | 2018 | |
| Impact of nutrition on inflammation, taupathy, and behavioral outcomes from chronic traumatic encephalopathy | Yu J, Zhu H, Taheri S, Mondy W, Perry S, Kindy MS | Journal of Neuroinflammation | 2018 | |
| Deoxycholate fractionation of fibronectin (FN) and biotinylation assay to measure recycled FN fibrils in epithelial cells | Varadaraj A, Magdaleno C, Mythreye K | Bio-protocol | 2018 | |
| Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer | Serrao A, Jenkins LM, Chumanevich AA, Horst B, Liang J, Gatza ML, Lee NY, Roninson IB, Broude EV, Mythreye K | Oncogene | 2018 | |
| Inhibin is a novel paracrine factor for tumor angiogenesis and metastasis | Singh P, Jenkins LM, Horst B, Alers V, Pradhan S, Kaur P, Srivastava T, Hempel N, Győrffy B, Broude EV, Lee NY, Mythreye K | Cancer Research | 2018 | |
| Dually modified transmembrane proteoglycans in development and disease | Jenkins LM, Horst B, Lancaster CL, Mythreye K | Cytokine & Growth Factor Reviews | 2018 | |
| Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1 | Alam A, Kung R, Kowal J, Mcleod RA, Tremp N, Broude EV, Roninson IB, Stahlberg H, Locher KP | Proceedings of the National Academy of Sciences of the United States of America | 2018 | |
| Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate
cellular survival
2018 Pilot Project Publication |
Chukwurah E, Patel RC | Scientific Reports | 2018 | |
| Dually modified transmembrane proteoglycans in development and disease | Jenkins LM, Horst B, Lancaster CL, Mythreye K | Cytokine & Growth Factor Reviews | 2017 | |
| Tris (1, 3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos | Dasgupta S, Vliet SM, Kupsco A, Leet JK, Altomare D, Volz DC | PeerJ | 2017 | |
| Succination of Protein Disulfide Isomerase Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes | Manuel AM, Walla MD, Faccenda A, Martin SL, Tanis RM, Piroli GG, Adam J, Kantor B, Mutus B, Townsend DM, Frizzell N | Antioxidants & Redox Signaling | 2017 | |
| CDK8/19 Mediator kinases potentiate induction of transcription by NFκB | Chen M, Liang J, Ji H, Yang Z, Altilia S, Hu B, Schronce A, McDermott MSJ, Schools GP, Lim CU, Oliver D, Shtutman MS, Lu T, Stark GR, Porter DC, Broude EV, Roninson IB | Proceedings of the National Academy of Sciences of the United States of America
|
2017 | |
| TGF-β triggers rapid fibrillogenesis via a novel TβRIIdependent fibronectin-trafficking mechanism | Varadaraj A, Jenkins LM, Singh P, Chanda A, Snider J, Lee NY, Amsalem-Zafran AR, Ehrlich M, Henis YI, Mythreye K | Molecular Biology of the Cell | 2017 | |
| Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen | Oliver D, Ji H, Liu P, Gasparian A, Gardiner E, Lee S, Zenteno A, Perinskaya LO, Chen M, Buckhaults P, Broude E, Wyatt MD, Valafar H, Pena E, Shtutman M | Scientific Reports | 2017 | |
| Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and dysregulated autophagy | Pan CC, Shah N, Kumar S, Wheeler SE, Cinti J, Hoyt DG, Beattie CE, An M, Mythreye K, Rakotondraibe LH, Lee NY | Oncotarget | 2017 | |
| Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer | McDermott MS, Chumanevich AA, Lim CU, Liang J, Chen M, Altilia S, Oliver D, Rae JM, Shtutman M, Kiaris H, Gyorffy B, Roninson IB, Broude EV | Oncotarget | 2017 | |
| Transgenerational attenuation of opioid self-administration as a consequence of adolescent morphine exposure | Vassoler FM, Oliver DJ, Wyse C, Blau A, Shtutman M, Turner JR, Byrnes EM | Neuropharmacology | 2017 | |
| Cellular Model of p21-Induced Senescence | Shtutman M, Chang BD, Schools GP, Broude EV | Methods in Molecular Biology | 2017 | |
| IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis | Zhang Y, Davis C, Shah S , Hughes D, Ryan JC, Altomare D, Pena MM | Molecular Carcinogenesis | 2017 | |
| Crystal structure of truncated human coatomer protein complex subunit ζ1 (Copζ1) | Lunev S, Semmelink MF, Xian JL, Ma KY, Leenders AJ, Domling AS, Shtutman M, Groves MR | Acta Crystallographica Section F | 2017 | |
| ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1
trans-activating response (TAR) element
2017 Pilot Project Publication |
Chukwurah E, Handy I, Patel RC | Biochemical Journal | 2017 | |
| Intranasal insulin in Alzheimer's Disease: Food for thought
2017 Pilot Project Publication |
Chapman CD, Schiöth HB, Grillo C, Benedict C | Neuropharmacology | 2017 | |
| Tribbles 3 regulates protein turnover in mouse skeletal muscle
2017 Pilot Project Publication |
Choi RH, McConahay A, Jeong H, McClellan JL, Hardee JP, Carson JA, Hirshman MF, Goodyear LJ, Koh HJ | Biochemical and Biophysical Research Communications | 2017 | |
| Altering the Proteoglycan State of Transforming Growth Factor β Type III Receptor (TβRIII)/Betaglycan Modulates Canonical Wnt/β-Catenin Signaling | Jenkins LM, Singh P, Varadaraj A, Lee NY, Shah S, Flores HV, O'Connell K, Mythreye K | Journal of Biological Chemistry | 2016 | |
| PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain | Hegde S, Ji H, Oliver D, Patel NS, Poupore N, Shtutman M, Kelly MP | Neuroscience | 2016 | |
| Activation of Mitofusin2 by Smad2-RIN1 Complex during Mitochondrial Fusion | Kumar S, Pan CC, Shah N, Wheeler SE, Hoyt KR, Hempel N, Mythreye K, Lee NY | Molecular Cell | 2016 | |
| A novel double-negative feedback loop between miR-489 and the HER2-SHP2- MAPK signaling axis regulates breast cancer cell proliferation and tumor growth | Patel Y, Shah N, Lee JS, Markoutsa E, Jie C, Liu S, Botbyl R, Reisman D, Xu P, Chen H | Oncotarget | 2016 | |
| Gold Nanosphere Gated Mesoporous Silica Nanoparticle Responsive to Near-Infrared Light and Redox Potential as a Theranostic Platform for Cancer Therapy | Cheng B, He H, Huang T, Berr SS, He J, Fan D, Zhang J, Xu P | Journal of Biomedical Nanotechnology | 2016 | |
| Tribbles 3 inhibits brown adipocyte differentiation and function by suppressing insulin signaling | Jeong HW, Choi RH, McClellan JL, Piroli GG, Frizzell N, Tseng YH, Goodyear LJ, Koh HJ | Biochemical and Biophysical Research Communications | 2016 | |
| Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome | Piroli GG, Manuel AM, Clapper AC, Walla MD, Baatz JE, Palmiter RD, Quintana A, Frizzell N | Molecular & Cellular Proteomics | 2016 | |
| A Critical Role for the GluA1 Accessory Protein, SAP97, in Cocaine Seeking
2016 Pilot Project Publication |
White S, Ortinski P, Friedman SH, Zhang L, Neve R, Kalb RG, Schmidt HD, Pierce RC | Neuropsychopharmacology | 2016 | |
| Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate
Reuptake
2016 Pilot Project Publication |
Zhou L, Anderson H, Arreola AC, Turner J, Ortinski PI | PLOS One | 2016 | |
| Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers | Rai R, Zhang F, Colavita K, Leu NA, Kurosaka S, Kumar A, Birnbaum MD, Gyorffy B, Dong DW, Shtutman M, Kashina A | Oncogene | 2015 | |
| Cancer cell-selective killing polymer/copper combination | He H, Altomare D, Ozer U, Xu H, Creek K, Chen H, Xu P | Biomaterials Science | 2015 | |
| Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia | Varadaraj A, Patel P, Serrao A, Bandyopadhay T, Lee NY, Jazaeri AA, Huang Z, Murphy SK, Mythreye K | Neoplasia | 2015 | |
| Purification of high-quality RNA from synthetic polyethylene glycol-based hydrogels | Gasparian A, Daneshian L, Ji H, Jabbari E, Shtutman M | Analytical Biochemistry | 2015 | |
| Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine | Gomez AM, Altomare D, Sun WL, Midde NM, Ji H, Shtutman M, Turner JR, Creek KE, Zhu J. | The International Journal of Neuropsychopharmacology | 2015 | |
| Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy | Pan CC, Kumar S, Shah N, Bloodworth JC, Hawinkels LJ, Mythreye K, Hoyt DG, Lee NY | Journal of Biological Chemistry | 2015 | |
| Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells | Levina E, Ji H, Chen M, Baig M, Oliver D, Ohouo P, Lim CU, Schools G, Carmack S, Ding Y, Broude EV, Roninson IB, Buttyan R, Shtutman M | Oncotarget | 2015 | |
| Dual secured nano-melittin for the safe and effective eradication of cancer cells. Journal of materials chemistry | Bei C, Bindu T, Remant KC, Peisheng X | Journal of Materials Chemistry B | 2015 | |
| The effect of glucose concentration and sodium phenylbutyrate treatment on mitochondrial bioenergetics and ER stress in 3T3-L1 adipocytes | Tanis RM, Piroli GG, Day SD, Frizzell N | Biochimica et Biophysica Acta | 2015 | |
| Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer | Broude EV, Gyorffy B, Chumanevich AA, Chen M, McDermott MS, Shtutman M, Catroppo JF, Roninson IB | Current Cancer Drug Targets | 2015 | |
| The Novel KV7.2/KV7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional
Roles in Guinea Pig Detrusor Smooth Muscle Excitability and Contractility
2015 Pilot Project Publication |
Provence A, Malysz J, Petkov, GV | Journal of Pharmacology and Experimental Therapeutics | 2015 | |
| Triple-responsive expansile nanogel for tumor and mitochondria targeted photosensitizer delivery | He H, Cattran AW, Nguyen T, Nieminen AL, Xu P | Biomaterials | 2014 | |
| Identification of protein succination as a novel modification of tubulin | Piroli GG, Manuel AM, Walla MD, Jepson MJ, Brock JW, Rajesh MP, Tanis RM, Cotham WE, Frizzell N | Biochemical Journal | 2014 |